DIALOG is an international, interdisciplinary research initiative dedicated to understanding the brain mechanisms underlying disorganised speech and language in people with severe mental disorders such as schizophrenia, bipolar disorder, and major depression. Speech disorganisation—often invisible and poorly understood—can significantly hinder social interaction and recovery for affected individuals.

By combining naturalistic speech analysis with cutting-edge neuroimaging and computational tools, including Large Language Models (LLMs), DIALOG aims to identify the neural signatures of disorganisation and uncover new, targeted interventions. Our approach is rooted in collaboration—with global experts, community partners, and people with lived experience of mental illness. 


Our Collaborative Work Groups

To tackle the complexity of disorganised speech and its neural underpinnings, DIALOG’s research is structured across five interconnected work groups. Each group focuses on a complementary aspect, from the fundamental brain and synaptic mechanisms to language metrics, connectivity, temporal dynamics, and clinical interventions. Ensuring a comprehensive, multidisciplinary approach to discovery and translation.



An International Project

DIALOG is powered by an extensive network of collaborators across 7 countries and over 12 institutions, including: 

We collaborate with leading experts in linguistics, psychiatry, neuroimaging, and AI to drive discovery and translation

What our team has been up to

News

Our Funder

DIALOG is supported by a WELLCOME trust grant